Article
Quantitative Analysis of Single-Nucleotide Polymorphism for Rapid Detection of TR34/L98H- and TR46/Y121F/T289A-Positive Aspergillus fumigatus Isolates Obtained from Patients in Iran from 2010 to 2014.
Antimicrobial agents and chemotherapy - 1 Jan 2016
Mohammadi Faezeh, Hashemi Seyed Jamal, Zoll Jan, Melchers Willem J G, Rafati Haleh, Dehghan Parvin, Rezaie Sasan, Tolooe Ali, Tamadon Yalda, van der Lee Henrich A, Verweij Paul E, Seyedmousavi Seyedmojtaba
Abstract excerpt
We employed an endpoint genotyping method to update the prevalence rate of positivity for the TR34/L98H mutation (a 34-bp tandem repeat mutation in the promoter region of the cyp51A gene in combination with a substitution at codon L98) and the TR46/Y121F/T289A mutation (a 46-bp tandem repeat mutation in the promoter region of the cyp51A gene in combination with substitutions at codons Y121 and T289) among...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.