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Article

Effect of Genetic Factors, Age and Sex on Levels of Circulating Extracellular Vesicles and Platelets.

International journal of molecular sciences - 13 Apr 2023

Orrù Valeria, Virdis Francesca, Marongiu Michele, Serra Valentina, Schlessinger David, Devoto Marcella, Cucca Francesco, Fiorillo Edoardo

Abstract excerpt

Extracellular vesicles (EVs) mediate cell interactions in biological processes, such as receptor activation or molecule transfer. Estimates of variation by age and sex have been limited by small sample size, and no report has assessed the contribution of genetic factors to levels of EVs. Here, we evaluated blood levels of 25 EV and 3 platelet traits in 974 individuals (933 genotyped) and reported the first...

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Source

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Identifiers

PMID: 37108346
DOI: 10.3390/ijms24087183
PMCID: PMC10138662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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