Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unmasking a novel disease gene NEO1 associated with autism spectrum disorders by a hemizygous deletion on chromosome 15 and a functional polymorphism.

Behavioural brain research - 1 Mar 2016

Siu Wai-Kwan, Lam Ching-Wan, Gao Wei-Wei, Vincent Tang Hei-Man, Jin Dong-Yan, Mak Chloe Miu

Abstract excerpt

BACKGROUND: Autism spectrum disorders (ASD) are neurodevelopmental disorders with a high degree of heritability, but the genetic basis is exceedingly heterogeneous. Microdeletions of chromosome 15q24 have been demonstrated to be recurrent genomic alterations in ASD patients. Of interest, neuronal migration genes are of particular relevance to the pathogenesis of ASD. NEO1 is located in 15q24 and encodes for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to Autism Spectrum Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genes, Recessive

Share to HEK293 Cells

Share to Mutation, Missense

Share to Nerve Tissue Proteins

Share to Receptors, Cell Surface

Source

Identifiers

PMID: 26518331
DOI: 10.1016/j.bbr.2015.10.041

Genes

NEO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unmasking a novel disease gene NEO1 associated with autism spectrum disorders by a hemizygous deletion on chromosome 15 and a functional polymorphism.PMID 26518331Read ↗

Refining critical regions in 15q24 microdeletion syndrome pertaining to autism.Semantic proximity Read ↗

Analyses of Human Genetic Data to Identify Clinically Relevant Domains of Neuroligins.Semantic proximity Read ↗

Functional significance of rare neuroligin 1 variants found in autism.Semantic proximity Read ↗

Shared susceptibility region on chromosome 15 between autism and catatonia.Semantic proximity Read ↗

Genetic dissection identifies Necdin as a driver gene in a mouse model of paternal 15q duplications.Semantic proximity Read ↗

Alterations in CDH15 and KIRREL3 in patients with mild to severe intellectual disability.Semantic proximity Read ↗

A novel 800 kb microduplication of chromosome 16q22.1 resulting in learning disability and epilepsy may explain phenotypic variability in a family with 15q13 microdeletion.Semantic proximity Read ↗

Association of oligodendrocytes differentiation regulator gene DUSP15 with autism.Semantic proximity Read ↗

A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologues.Semantic proximity Read ↗

Deletion polymorphism in the coding region of the human NESP55 alternative transcript of GNAS1.Semantic proximity Read ↗

NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy.Semantic proximity Read ↗

2p15-p16.1 microdeletion syndrome: molecular characterization and association of the OTX1 and XPO1 genes with autism spectrum disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.