Article
Distinguishing benign from pathologic TH2 immunity in atopic children.
The Journal of allergy and clinical immunology - 1 Feb 2016
Holt Patrick G, Strickland Deborah, Bosco Anthony, Belgrave Danielle, Hales Belinda, Simpson Angela, Hollams Elysia, Holt Barbara, Kusel Merci, Ahlstedt Staffan, Sly Peter D, Custovic Adnan
Abstract excerpt
BACKGROUND: Although most children with asthma and rhinitis are sensitized to aeroallergens, only a minority of sensitized children are symptomatic, implying the underlying operation of efficient anti-inflammatory control mechanisms. OBJECTIVE: We sought to identify endogenous control mechanisms that attenuate expression of IgE-associated responsiveness to aeroallergens in sensitized children. METHODS: In 3...
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