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Article

A distinct molecular mutational profile and its clinical impact in essential thrombocythemia and primary myelofibrosis patients.

BMC cancer - 12 Mar 2020

Zaidi Uzma, Sufaida Gul, Rashid Munazza, Kaleem Bushra, Maqsood Sidra, Mukry Samina Naz, Khan Rifat Zubair Ahmed, Munzir Saima, Borhany Munira, Shamsi Tahir Sultan

Abstract excerpt

BACKGROUND: Classical MPNs including ET and PMF have a chronic course and potential for leukaemic transformation. Timely diagnosis is obligatory to ensure appropriate management and positive outcomes. The aim of this study was to determine the mutational profile, clinical characteristics and outcome of ET and PMF patients in Pakistani population. METHODS: This was a prospective observational study conducted...

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PMID: 32164591
DOI: 10.1186/s12885-020-6700-3
PMCID: PMC7069043

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