Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced SLC27A2 induces cisplatin resistance in lung cancer stem cells by negatively regulating Bmi1‐ABCG2 signaling

29 Oct 2015

Abstract excerpt

Platinum‐based chemotherapies have long been used as a standard treatment in non‐small cell lung cancer (NSCLC). However, cisplatin resistance is a major problem that restricts the use of cisplatin. Lung cancer stem cells (LCSCs) represent a subpopulation that is responsible for chemo‐resistance. We aim to investigate the biological function of SLC27A2 and its underlying mechanisms in regulating chemo‐resistance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Epigenetics and DNA Methylation
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26513225
DOI: 10.1002/mc.22430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced SLC27A2 induces cisplatin resistance in lung cancer stem cells by negatively regulating Bmi1‐ABCG2 signalingPMID 26513225Read ↗

SLC2A1 promotes chemo-immunotherapy resistance in lung adenocarcinoma by modulating the AKT signaling pathwaySemantic proximity Read ↗

DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4Semantic proximity Read ↗

Lung cancer stem cells: The root of resistance.Semantic proximity Read ↗

The effects and mechanisms of SLC34A2 on tumorigenicity in human non-small cell lung cancer stem cellsSemantic proximity Read ↗

Mechanistic Exploration of Cancer Stem Cell Marker Voltage-Dependent Calcium Channel α2δ1 Subunit-mediated Chemotherapy Resistance in Small-Cell Lung CancerSemantic proximity Read ↗

Abnormal genome-wide DNA methylation induced by cisplatin may contribute to the chemo-resistance of human small cell lung cancerSemantic proximity Read ↗

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?Semantic proximity Read ↗

Regulation of cisplatin resistance in lung cancer by epigenetic mechanismsSemantic proximity Read ↗

NOTCH1 Signaling Regulates Self-Renewal and Platinum Chemoresistance of Cancer Stem–like Cells in Human Non–Small Cell Lung CancerSemantic proximity Read ↗

Autophagy-mediated ID1 turnover dictates chemo-resistant fate in ovarian cancer stem cellsSemantic proximity Read ↗

Applications of Machine Learning to Predict Cisplatin Resistance in Lung CancerSemantic proximity Read ↗

Integrated analysis reveals critical cisplatin-resistance regulators E2F7 contributed to tumor progression and metastasis in lung adenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.