Article
[HPV-associated head and neck cancer : mutational signature and genomic aberrations].
HNO - 1 Nov 2015
Wagner S, Würdemann N, Hübbers C, Reuschenbach M, Prigge E-S, Wichmann G, Hess J, Dietz A, Dürst M, Tinhofer I, von Knebel-Döberitz M, Wittekindt C, Klussmann J P
Abstract excerpt
A significantly increasing proportion of oropharyngeal head and neck carcinomas (OSCC) in North America and Europe are associated with human papillomavirus (HPV) infections. HPV-related OSCC is regarded as a distinct tumor type with regard to its cellular, biologic, and clinical characteristics. Patients with HPV-related OSCC have significantly better local control, but higher rates of regional lymph node and...
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