Article
Upcoming translational challenges for uveal melanoma.
British journal of cancer - 3 Nov 2015
Amirouchene-Angelozzi Nabil, Schoumacher Marie, Stern Marc-Henri, Cassoux Nathalie, Desjardins Laurence, Piperno-Neumann Sophie, Lantz Olivier, Roman-Roman Sergio
Abstract excerpt
The past few years have witnessed major advances in the understanding of the molecular landscape of uveal melanoma (UM). The discovery of a mutational background that is completely different from the one of skin melanoma has granted to UM a stand-alone status. The absence of effective therapy for metastatic disease offers now a chessboard for targeted therapy but at the same time urges preclinical science to...
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