Article
The relationship of miR-146a gene polymorphism with carotid atherosclerosis in Chinese patients with type 2 diabetes mellitus.
Thrombosis research - 1 Dec 2015
Shen Jing, Zhang Min, Sun Mingfang, Tang Kang, Zhou Bo
Abstract excerpt
OBJECTIVE: Atherosclerosis (AS) is regarded as the major cause of disability and death in diabetic patients. However, its precise pathogenesis is not entirely clear. Recent genome-wide association studies (GWAS) have revealed AS is related to some epigenetic changes. This study aimed to investigate the possible associations of miR-146a and transcriptional coactivator p300 polymorphisms with carotid...
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