Article
Phenoscape: Identifying Candidate Genes for Evolutionary Phenotypes.
Molecular biology and evolution - 1 Jan 2016
Edmunds Richard C, Su Baofeng, Balhoff James P, Eames B Frank, Dahdul Wasila M, Lapp Hilmar, Lundberg John G, Vision Todd J, Dunham Rex A, Mabee Paula M, Westerfield Monte
Abstract excerpt
Phenotypes resulting from mutations in genetic model organisms can help reveal candidate genes for evolutionarily important phenotypic changes in related taxa. Although testing candidate gene hypotheses experimentally in nonmodel organisms is typically difficult, ontology-driven information systems can help generate testable hypotheses about developmental processes in experimentally tractable organisms. Here, we...
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