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Article

More than just orphans: are taxonomically-restricted genes important in evolution?

Trends in genetics : TIG - 1 Sept 2009

Khalturin Konstantin, Hemmrich Georg, Fraune Sebastian, Augustin René, Bosch Thomas C G

Abstract excerpt

Comparative genome analyses indicate that every taxonomic group so far studied contains 10-20% of genes that lack recognizable homologs in other species. Do such 'orphan' or 'taxonomically-restricted' genes comprise spurious, non-functional ORFs, or does their presence reflect important evolutionary processes? Recent studies in basal metazoans such as Nematostella, Acropora and Hydra have shed light on the...

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PMID: 19716618
DOI: 10.1016/j.tig.2009.07.006

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