Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased expression of the APOA1-APOC3-APOA4 gene cluster is associated with risk of Alzheimer's disease.

Drug design, development and therapy - 1 Jan 2015

Lin Qiao, Cao Yunpeng, Gao Jie

Abstract excerpt

BACKGROUND: Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. Therefore, this gene cluster may be related to the risk of AD. PATIENTS AND METHODS: A total of 147 AD patients and 160 healthy controls were randomly recruited from June 2013 to August 2014. APOA1, APOC3, and APOA4 levels were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-I
Share to Apolipoprotein C-III
Share to Apolipoproteins A

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Down-Regulation

Share to Enzyme-Linked Immunosorbent Assay

Share to Health Status

Share to Real-Time Polymerase Chain Reaction

Share to Surveys and Questionnaires

Source

Open in PubMed Open full text

Identifiers

PMID: 26491253
DOI: 10.2147/DDDT.S89279
PMCID: PMC4598222

Genes

APOA1
APOA4
APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased expression of the APOA1-APOC3-APOA4 gene cluster is associated with risk of Alzheimer's disease.PMID 26491253Read ↗

Association between APOC1 polymorphism and Alzheimer's disease: a case-control study and meta-analysis.Semantic proximity Read ↗

Apolipoprotein E gene polymorphism and Alzheimer's disease in Chinese population: a meta-analysis.Semantic proximity Read ↗

Protective effect of Apolipoprotein E epsilon 3 on sporadic Alzheimer's Disease in Chinese population: A Meta-AnalysisSemantic proximity Read ↗

Correlation of rs9331888 polymorphism with Alzheimer's disease among Caucasian and Chinese populations: a meta-analysis and systematic review.Semantic proximity Read ↗

Association of plasma apolipoproteins and levels of inflammation-related factors with different stages of Alzheimer’s disease: a cross-sectional studySemantic proximity Read ↗

Association between apolipoprotein E polymorphism and serum lipid and apolipoprotein levels with Alzheimer's disease.Semantic proximity Read ↗

Protective effect of apolipoprotein E epsilon 3 on sporadic Alzheimer's disease in the Chinese population: a meta-analysis.Semantic proximity Read ↗

APOE and APOC1 gene polymorphisms are associated with cognitive impairment progression in Chinese patients with late-onset Alzheimer′s diseaseSemantic proximity Read ↗

Prevalence of Apolipoprotein E Polymorphisms in Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Elderly: A Northern Greece Study.Semantic proximity Read ↗

Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: cohort studies and meta-analyses of 362,338 individuals.Semantic proximity Read ↗

Clusterin, TNF-α, and IL-6 polymorphism and implications on Alzheimer’s disease risk determination in Saudi populationSemantic proximity Read ↗

Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.