Article
Fc Gamma Receptor IIA (CD32A) R131 Polymorphism as a Marker of Genetic Susceptibility to Sepsis.
Inflammation - 1 Apr 2016
Beppler Jaqueline, Koehler-Santos Patrícia, Pasqualim Gabriela, Matte Ursula, Alho Clarice Sampaio, Dias Fernando Suparregui, Kowalski Thayne Woycinck, Velasco Irineu Tadeu, Monteiro Renato C, Pinheiro da Silva Fabiano
Abstract excerpt
Sepsis is a devastating disease that can affect humans at any time between neonates and the elderly and is associated with mortality rates that range from 30 to 80%. Despite intensive efforts, its treatment has remained the same over the last few decades. Fc receptors regulate multiple immune responses and have been investigated in diverse complex diseases. FcγRIIA (CD32A) is an immunoreceptor, tyrosine-based...
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