Article
FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target.
Radiation research - 1 Nov 2015
Horton Janet K, Siamakpour-Reihani Sharareh, Lee Chen-Ting, Zhou Ying, Chen Wei, Geradts Joseph, Fels Diane R, Hoang Peter, Ashcraft Kathleen A, Groth Jeff, Kung Hsiu-Ni, Dewhirst Mark W, Chi Jen-Tsan A
Abstract excerpt
Although a standardized approach to radiotherapy has been used to treat breast cancer, regardless of subtype (e.g., luminal, basal), recent clinical data suggest that radiation response may vary significantly among subtypes. We hypothesized that this clinical variability may be due, in part, to differences in cellular radiation response. In this study, we utilized RNA samples for microarray analysis from two...
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