Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brca1 Mutations Enhance Mouse Reproductive Functions by Increasing Responsiveness to Male-Derived Scent.

PloS one - 1 Jan 2015

Liu Ying, Pike Malcolm C, Wu Nancy, Lin Yvonne G, Mucowski Sara, Punj Vasu, Tang Yuan, Yen Hai-Yun, Stanczyk Frank Z, Enbom Elena, Austria Theresa, Widschwendter Martin, Maxson Robert, Dubeau Louis

Abstract excerpt

We compared the gene expression profiles of ovarian granulosa cells harboring either mutant or wild type Brca1 to follow up on our earlier observation that absence of a functional Brca1 in these important regulators of menstrual/estrous cycle progression leads to prolongation of the pre-ovulatory phase of the estrous cycle and to increased basal levels of circulating estradiol. Here we show that ovarian granulosa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to Granulosa Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoenzyme Techniques

Share to Odorants

Share to Real-Time Polymerase Chain Reaction

Share to Receptors, Odorant

Share to Reproduction

Source

Open in PubMed Open full text

Identifiers

PMID: 26488398
DOI: 10.1371/journal.pone.0139013
PMCID: PMC4619541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brca1 Mutations Enhance Mouse Reproductive Functions by Increasing Responsiveness to Male-Derived Scent.PMID 26488398Read ↗

Reproductive biology of female <i>Bmal1</i> null miceSemantic proximity Read ↗

Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer.Semantic proximity Read ↗

Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.Semantic proximity Read ↗

Requirement of <i>Lim1</i> for female reproductive tract developmentSemantic proximity Read ↗

The short estrous cycle of mice may influence the effect of BRCA1 mutations.Semantic proximity Read ↗

Critical Roles of the Circadian Transcription Factor BMAL1 in Reproductive Endocrinology and FertilitySemantic proximity Read ↗

An olfactory bulb GnRH neuronal population translates social relevant odors into reproductive behavior in male miceSemantic proximity Read ↗

A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State.Semantic proximity Read ↗

The paternally expressed gene Peg3 regulates sexual experience-dependent preferences for estrous odors.Semantic proximity Read ↗

A battery of olfactory-based screens for phenotyping the social and sexual behaviors of mice.Semantic proximity Read ↗

A functional circuit underlying male sexual behaviour in the female mouse brain.Semantic proximity Read ↗

Impaired Steroidogenesis and Implantation Failure in Bmal1−/− MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.