Analysis of tumorigenesis and immunological role of LTBP2: a potential predictor for immunotherapy

Abstract excerpt

<title>Abstract</title> <p>Latent Transforming Growth Factor-β-1 Binding Protein-2 (LTBP-2), a member of the LTBP-fibrillin superfamily of extracellular matrix proteins, has been implicated in promoting TGF-β expression and secretion. However, its precise role in tumorigenesis remains ambiguous. This study comprehensively investigates the potential impact of LTBP2 on patient prognosis and response to immune thera...

Topics

Open a Topic to create a Post that cites this publication.

• Carcinogenesis
• Ferroptosis and cancer prognosis
• Inflammation
• MAP Kinase Kinase Kinases
• MAP Kinase Signaling System
• Molecular Targeted Therapy
• Protein Kinase Inhibitors
• TGF-β signaling in diseases

Identifiers and source

Literature Corpus work

0f53ab80-d635-5cdd-a66e-89d23b65c191

DOI

10.21203/rs.3.rs-3933887/v1