Article
ANALYSIS OF POLYMORPHISMS IN THE INTERLEUKIN 18 GENE PROMOTOR (-137 G/C AND -607 C/A) IN PATIENTS INFECTED WITH HEPATITIS C VIRUS FROM THE BRAZILIAN AMAZON.
Arquivos de gastroenterologia - 1 Jan 2000
Santos Kemper Nunes dos, Almeida Marcella Kelly Costa de, Fecury Amanda Alves, Costa Carlos Araújo da, Martins Luísa Caricio
Abstract excerpt
BACKGROUND: The hepatitis C virus has been recognized as the leading cause of chronic liver disease in the world. Host genetic factors have been implicated in the persistence of hepatitis C virus infection. Single nucleotide polymorphisms at positions -607 C/A (rs1946518) and -137 G/C (rs187238) in the IL-18 gene promoter have been suggested to be associated with delayed hepatitis C virus clearance and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
