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Article

Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma.

Oncotarget - 3 May 2016

Wang Zifeng, Xie Jiajun, Yan Min, Wang Jing, Wang Xi, Zhang Jialiang, Zhang Yan, Li Pengfei, Lei Xinxing, Huang Qitao, Lin Suxia, Guo Xiang, Liu Quentin

Abstract excerpt

Mechanism for the malignant phenotype of nasopharyngeal carcinoma (NPC) remains poorly understood. Epstein-Barr virus (EBV) consistently appears in nearly all malignant NPC patient samples, suggesting the strong etiological link between the malignant phenotype and EBV infection. Here we found that the EBV-encoded latent membrane protein (LMP1) enhanced cell growth, motility, invasion and xenograft tumor growth of...

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Source

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Identifiers

PMID: 27049918
DOI: 10.18632/oncotarget.8503
PMCID: PMC5042013

Genes

ATOH8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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