Article
Analysis of common variations in tumor-suppressor genes on chr1p36 among Caucasian women with endometriosis.
Gynecologic oncology - 1 Nov 2012
Falconer Henrik, Sundqvist Johanna, Xu Hong, Vodolazkaia Alexandra, Fassbender Amelie, Kyama Cleophas, Bokor Attila, D'Hooghe Thomas M
Abstract excerpt
OBJECTIVE: Epidemiological data indicate that endometriosis increases the risk of epithelial ovarian cancer (EOC), but the mechanism of cancer transition is unknown. Results from genome-wide association studies (GWAS) and transcriptome sequencing have demonstrated that genes located in the 1p36 region are important in both endometriosis and endometriosis-associated cancer development. Therefore, we tested the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
