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Article

cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.

Behavioural brain research - 15 Jan 2016

Nikaido Yoshikazu, Yamada Junko, Migita Keisuke, Shiba Yuko, Furukawa Tomonori, Nakashima Toshihiro, Ueno Shinya

Abstract excerpt

Several green leaf volatiles have anxiolytic/antidepressant properties and attenuate adrenocortical stress response in rodents. However, it remains unknown whether a mixture of cis-3-hexenol and trans-2-hexenal so-called 'green odor (GO)' affects fear-associated post-traumatic stress disorder (PTSD)-like behavior. In the present study, fear memory of the initial conditioning stimulus was stably maintained by...

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Source

Identifiers

PMID: 26475511
DOI: 10.1016/j.bbr.2015.10.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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