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Article

Murine Norovirus Infection Variably Alters Atherosclerosis in Mice Lacking Apolipoprotein E.

Comparative medicine - 1 Oct 2015

Hsu Charlie C, Paik Jisun, Brabb Thea L, O'Brien Kevin D, Kim Jinkyu, Sullivan Brittany G, Hudkins Kelly L, Seamons Audrey, Finley Jennifer C, Meeker Stacey M, Maggio-Price Lillian

Abstract excerpt

Macrophages play a key role in the development of atherosclerosis. Murine noroviruses (MNV) are highly prevalent in research mouse colonies and infect macrophages and dendritic cells. Our laboratory found that MNV4 infection in mice lacking the LDL receptor alters the development of atherosclerosis, potentially confounding research outcomes. Therefore, we investigated whether MNV4 likewise altered atherosclerosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26473341
PMCID: PMC4617328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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