Article
Pharmacogenetic Biomarkers Predictive of the Pharmacokinetics and Pharmacodynamics of Immunosuppressive Drugs.
Therapeutic drug monitoring - 1 Apr 2016
Picard Nicolas, Bergan Stein, Marquet Pierre, van Gelder Teun, Wallemacq Pierre, Hesselink Dennis A, Haufroid Vincent
Abstract excerpt
In association with therapeutic drug monitoring of immunosuppressive drugs, pharmacogenetics has rapidly emerged as an additional tool to refine dose selection or, more interestingly to select, a priori, the first dose to administer. Pharmacogenetic biomarkers are now readily available in most transplantation centers, at a limited cost and within a limited analytical time frame, which make them compatible with...
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