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Article

HPIP promotes thyroid cancer cell growth, migration and EMT through activating PI3K/AKT signaling pathway.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2015

Wang Shun-chang, Chai Da-sen, Chen Chuan-bo, Wang Zheng-ye, Wang Lei

Abstract excerpt

Hematopoietic pre-B cell leukemia transcription factor (PBX)-interacting protein (HPIP), a co-repressor for the transcription factor PBX, is a nucleo-cytoplasmic shuttling protein. Increasing evidence suggests that HPIP is an oncogene which is frequently overexpressed in many human carcinomas. However, the role of HPIP in thyroid carcinoma is still unclear. Therefore, in this study, we investigated the role of...

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Identifiers

PMID: 26463629
DOI: 10.1016/j.biopha.2015.08.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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