[Histologic subtyping of poorly-differentiated solid lung cancer with molecular testing for epidermal growth factor receptor mutation and ALK gene rearrangement: an analyses of 167 cases].

doi:10.3760/cma.j.issn.0529-5807.2018.06.009

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Article

[Histologic subtyping of poorly-differentiated solid lung cancer with molecular testing for epidermal growth factor receptor mutation and ALK gene rearrangement: an analyses of 167 cases].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 Jun 2018

Fang F, Wang Y X, Hu S T, Yang L, Di J, Liu D G, Lyu N

Abstract excerpt

Objective: To study the histological subtyping of poorly differentiated solid lung cancer by using immunohistochemistry and mucin staining along with analysis of epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) gene rearrangement. Methods: Among 827 cases of non-small cell lung cancer at Beijing Hospital from April 2014 to April 2017, 167 cases of solid poorly differentiated...

Topics

Adenocarcinoma
Adult
Aged
Anaplastic Lymphoma Kinase
Carcinoma, Adenosquamous
Carcinoma, Neuroendocrine
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
DNA Mutational Analysis
ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Exons

Female

Gene Rearrangement

Genes, erbB-1

Humans

Immunohistochemistry

In Situ Hybridization, Fluorescence

Lung Neoplasms

Source

Open in PubMed

Identifiers

PMID: 29886587
DOI: 10.3760/cma.j.issn.0529-5807.2018.06.009

Genes

ALK
EGFR
TTF1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29886587-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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