Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.

PloS one - 1 Jan 2015

Kumanomidou Taichi, Nishio Kazuya, Takagi Kenji, Nakagawa Tomomi, Suzuki Atsuo, Yamane Takashi, Tokunaga Fuminori, Iwai Kazuhiro, Murakami Arisa, Yoshida Yukiko, Tanaka Keiji, Mizushima Tsunehiro

Abstract excerpt

The Skp1-Cul1-F-box protein (SCF) complex catalyzes protein ubiquitination in diverse cellular processes and is one of the best-characterized ubiquitin ligases. F-box proteins determine the substrate specificities of SCF ubiquitin ligases. Among these, Fbs1/FBG1/FBXO2, Fbs2/FBG2/FBXO6, and Fbs3/FBG5/FBXO27 recognize the N-glycans of glycoproteins, whereas FBG3/FBXO44 has no sugar-binding activity, despite the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Crystallography, X-Ray

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to F-Box Proteins

Share to Glycoproteins

Share to Mutant Proteins

Share to Ribonucleases

Share to S-Phase Kinase-Associated Proteins

Share to Substrate Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 26460611
DOI: 10.1371/journal.pone.0140366
PMCID: PMC4603797

Genes

FBXO2
FBXO27
FBXO44
FBXO6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.PMID 26460611Read ↗

Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase.Semantic proximity Read ↗

Lectin-Type Ubiquitin Ligase Subunits: Fbs Proteins and Their Applications for Use.Semantic proximity Read ↗

Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.Semantic proximity Read ↗

Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.Semantic proximity Read ↗

The FBXL family of F-box proteins: variations on a themeSemantic proximity Read ↗

Ancestral protein reconstruction reveals the mechanism of substrate specificity in FN3K-mediated deglycationSemantic proximity Read ↗

Ancestral protein reconstruction reveals the mechanism of substrate specificity in FN3K-mediated deglycationSemantic proximity Read ↗

An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides.Semantic proximity Read ↗

F-box proteins: more than baits for the SCF?Semantic proximity Read ↗

A non-Golgi alpha 1,2-fucosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium.Semantic proximity Read ↗

Fbs1 protects the malfolded glycoproteins from the attack of peptide:N-glycanase.Semantic proximity Read ↗

Structural and functional insights into the B30.2/SPRY domain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.