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Article

The eQTL-missense polymorphisms of APOBEC3H are associated with lung cancer risk in a Han Chinese population.

Scientific reports - 13 Oct 2015

Zhu Meng, Wang Yuzhuo, Wang Cheng, Shen Wei, Liu Jia, Geng Liguo, Cheng Yang, Dai Juncheng, Jin Guangfu, Ma Hongxia, Hu Zhibin, Shen Hongbing

Abstract excerpt

APOBEC (Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) enzymes may involve in mutagenic processes in multiple cancer types, including lung cancer. APOBEC family of cytidine deaminases induces base substitutions with a stringent TCW motif, which is widespread in multiple human cancers. We hypothesized that common missense variants in coding regions of APOBEC genes might damage the structure of...

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Source

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Identifiers

PMID: 26459911
DOI: 10.1038/srep14969
PMCID: PMC4602211

Genes

APOBEC1
APOBEC2
APOBEC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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