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Molecular and Functional Characterization of ssDNA Aptamers that Specifically Bind Leishmania infantum PABP

12 Oct 2015

Abstract excerpt

SUMMARY: A poly (A)-binding protein from Leishmania infantum (LiPABP) has been recently cloned and characterized in our laboratory. Although this protein shows a very high homology with PABPs from other eukaryotic organisms including mammals and other parasites, exist divergences along the sequence that convert them in potential diagnostic markers and/or therapeutics targets. Aptamers are oligonucleotide ligands...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 26457419
DOI: 10.1371/journal.pone.0140048

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