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Comprehensive Identification of mRNA-Binding Proteins of Leishmania donovani by Interactome Capture

30 Jan 2017

Abstract excerpt

Leishmania are unicellular eukaryotes responsible for leishmaniasis in humans. Like other trypanosomatids, leishmania regulate protein coding gene expression almost exclusively at the post-transcriptional level with the help of RNA binding proteins (RBPs). Due to the presence of polycystronic transcription units, leishmania do not regulate RNA polymerase II-dependent transcription initiation. Recent evidence...

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PMID: 28135300
DOI: 10.1371/journal.pone.0170068

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