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<i>Leishmania infantum</i> LeIF protein is an ATP‐dependent RNA helicase and an eIF4A‐like factor that inhibits translation in yeast

16 Oct 2006

Abstract excerpt

LeIF, a Leishmania protein similar to the eukaryotic initiation factor eIF4A, which is a prototype of the DEAD box protein family, was originally described as a Th1-type natural adjuvant and as an antigen that induces an IL12-mediated Th1 response in the peripheral blood mononuclear cells of leishmaniasis patients. This study aims to characterize this protein by comparative biochemical and genetic analysis with...

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PMID: 17087726
DOI: 10.1111/j.1742-4658.2006.05506.x

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