Article
Clinical influence of cancer stem cells on residual disease after preoperative chemoradiotherapy for rectal cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2016
Yoon Ghilsuk, Kim Sol-Min, Kim Hye Jin, Seo An Na
Abstract excerpt
We evaluated the clinical influence of cancer stem cells (CSCs) on residual disease after preoperative chemoradiotherapy (CRT) in patients with rectal cancer. The surgical specimens of 145 patients with residual rectal cancer after preoperative CRT were assessed. To identify CSCs, immunohistochemistry was performed using their surrogate makers (CD44 and aldehyde dehydrogenase 1 [ALDH1]) in full section tissues....
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