Article
Cancer stem cell phenotype relates to radio-chemotherapy outcome in locally advanced squamous cell head-neck cancer.
British journal of cancer - 28 Feb 2012
Koukourakis M I, Giatromanolaki A, Tsakmaki V, Danielidis V, Sivridis E
Abstract excerpt
BACKGROUND: Cancer stem cells (CSCs) tend to repopulate malignant tumours during radiotherapy and, therefore, prolongation of the overall treatment time may result in radiotherapy failure. Thus, an estimate of the number of CSCs in tumour biopsies may prove most useful in predicting resistance to...
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