Article
Functional promoter polymorphisms of the receptor for advanced glycation end products in children and adolescents with type 1 diabetes.
Molecular and cellular probes - 1 Dec 2015
Gomes Letícia Carneiro, Welter Marciane, Gobor Luiza Cristina, Santos-Weiss Izabella Castilhos Ribeiro, França Suzana Nesi, Alberton Dayane, Picheth Geraldo, Rego Fabiane Gomes
Abstract excerpt
RAGE promoter polymorphisms are associated with increases in RAGE expression. A case-control association study was conducted involving a Euro-Brazilian population of children and adolescents with type 1 diabetes (n = 90) and healthy controls (n = 105), which were matched by sex and age. Genotyping by PCR-RFLP the -429T>C (rs1800625), -374T>A (rs1800624), and 63 bp deletion/insertion (-407 to -345 bp) showed no...
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