Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Systematic Review of Phenotypic Features Associated With Cardiac Troponin I Mutations in Hereditary Cardiomyopathies.

The Canadian journal of cardiology - 1 Nov 2015

Mogensen Jens, Hey Thomas, Lambrecht Sascha

Abstract excerpt

BACKGROUND: Genetic investigations have established that mutations in proteins of the contractile unit of the myocardium, known as the sarcomere, may be associated with hypertrophic cardiomyopathy (HCM), restrictive cardiomyopathy (RCM), and dilated cardiomyopathy (DCM). It has become clinical practice to offer genetic testing in affected individuals to identify causative mutations, which provides the basis for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathies
Share to DNA
Share to TNNI3 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Genotype

Share to Mutation

Share to Phenotype

Share to Troponin I

Source

Identifiers

PMID: 26440512
DOI: 10.1016/j.cjca.2015.06.015

Genes

TNNI3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Systematic Review of Phenotypic Features Associated With Cardiac Troponin I Mutations in Hereditary Cardiomyopathies.PMID 26440512Read ↗

Frequency and clinical expression of cardiac troponin I mutations in 748 consecutive families with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Inherited cardiomyopathies caused by troponin mutations.Semantic proximity Read ↗

Molecular and Cellular Aspects of Troponin CardiomyopathiesSemantic proximity Read ↗

Recurrent and founder mutations in the Netherlands: cardiac Troponin I (TNNI3) gene mutations as a cause of severe forms of hypertrophic and restrictive cardiomyopathySemantic proximity Read ↗

Spectrum and clinical manifestations of mutations in genes responsible for hypertrophic cardiomyopathy.Semantic proximity Read ↗

Low prevalence and variable clinical presentation of troponin I and troponin T gene mutations in hypertrophic cardiomyopathy.Semantic proximity Read ↗

Cardiac troponin I mutations in Australian families with hypertrophic cardiomyopathy: clinical, genetic and functional consequences.Semantic proximity Read ↗

A systematic review and meta-analysis of genotype-phenotype associations in patients with hypertrophic cardiomyopathy caused by sarcomeric protein mutations.Semantic proximity Read ↗

Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Inherited cardiomyopathies as a troponin disease.Semantic proximity Read ↗

Troponin mutations in cardiomyopathies.Semantic proximity Read ↗

Sarcomeric hypertrophic cardiomyopathy: genetic profile in a Portuguese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.