Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A systematic review and meta-analysis of genotype-phenotype associations in patients with hypertrophic cardiomyopathy caused by sarcomeric protein mutations.

Heart (British Cardiac Society) - 1 Dec 2013

Lopes Luís R, Rahman M Shafiqur, Elliott Perry M

Abstract excerpt

BACKGROUND: The genetic basis of familial hypertrophic cardiomyopathy (HCM) is well described, but the relation between genotype and clinical phenotype is still poorly characterised. OBJECTIVE: To summarise and critically review the current literature on genotype-phenotype associations in patients with HCM and to perform a meta-analysis on selected clinical features. DATA SOURCES: PubMed/Medline was searched up...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Myosins
Share to Cardiomyopathy, Hypertrophic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to Global Health

Share to Prevalence

Share to Troponin

Source

Identifiers

PMID: 23674365
DOI: 10.1136/heartjnl-2013-303939

Genes

SCD
MYBPC3
MYH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A systematic review and meta-analysis of genotype-phenotype associations in patients with hypertrophic cardiomyopathy caused by sarcomeric protein mutations.PMID 23674365Read ↗

Genetic determinants of the phenotype in a Swedish cohort of patients with hypertrophic cardiomyopathySemantic proximity Read ↗

Clinical outcomes associated with sarcomere mutations in hypertrophic cardiomyopathy: a meta-analysis on 7675 individuals.Semantic proximity Read ↗

Genotype-Phenotype Correlations Identify Phenotypic Differences in Sarcomere Mutation-Positive Hypertrophic Cardiomyopathy in the NHLBI HCM RegistrySemantic proximity Read ↗

Genetics of hypertrophic cardiomyopathy: A review of current state.Semantic proximity Read ↗

Diagnostic validity and clinical utility of genetic testing for hypertrophic cardiomyopathy: a systematic review and meta-analysis.Semantic proximity Read ↗

Characteristics and outcomes associated with sarcomere mutations in patients with hypertrophic cardiomyopathy: A systematic review and meta-analysis.Semantic proximity Read ↗

Hypertrophic cardiomyopathy: the genetic determinants of clinical disease expression.Semantic proximity Read ↗

Sarcomeric genotyping in hypertrophic cardiomyopathy.Semantic proximity Read ↗

Genotype-phenotype associations in sarcomeric hypertrophic cardiomyopathy associated with mutations in the MYBPC3 gene: Systematic review and meta-analysis.Semantic proximity Read ↗

Hypertrophic Cardiomyopathy: An Overview of Genetics and ManagementSemantic proximity Read ↗

Pathogenic genes and clinical prognosis in hypertrophic cardiomyopathySemantic proximity Read ↗

Phenotypic Expression and Outcomes in Individuals With Rare Genetic Variants of Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.