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Article

Spectrum and clinical manifestations of mutations in genes responsible for hypertrophic cardiomyopathy.

Acta cardiologica - 1 Feb 2012

Curila Karol, Benesova Lucie, Penicka Martin, Minarik Marek, Zemanek David, Veselka Josef, Widimsky Petr, Gregor Pavel

Abstract excerpt

INTRODUCTION: Hypertrophic cardiomyopathy (HCM) is a cardiovascular disease with autosomal dominant inheritance. It is caused by mutations in the genes coding for structural and/or regulatory proteins found in the sarcomere of cardiomyocytes. A group of genes, including the heavy chain of beta-myosin (MYH7), myosin binding protein C (MYBPC3), cardiac troponin I (TNNI3) and cardiac troponin T (TNNT2) are...

Topics

Adult
Aged
Cardiomyopathy, Hypertrophic
Humans
Middle Aged
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22455086
DOI: 10.1080/ac.67.1.2146562

Genes

MYBPC3
MYH7
TNNI3
TNNT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Spectrum and clinical manifestations of mutations in genes responsible for hypertrophic cardiomyopathy.PMID 22455086Read ↗

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