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Article

HES-Mediated Repression of Pten in Caenorhabditis elegans.

G3 (Bethesda, Md.) - 4 Oct 2015

Chou Han Ting, Vazquez Raymarie Gomez, Wang Kun, Campbell Richard, Milledge Gaolin Zheng, Walthall Walter W, Johnson Casonya M

Abstract excerpt

The hairy/enhancer-of-split (HES) group of transcription factors controls embryonic development, often by acting downstream of the Notch signaling pathway; however, little is known about postembryonic roles of these proteins. In Caenorhabditis elegans, the six proteins that make up the REF-1 family are considered to be HES orthologs that act in both Notch-dependent and Notch-independent pathways to regulate...

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Source

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Identifiers

PMID: 26438299
DOI: 10.1534/g3.115.019463
PMCID: PMC4683635

Genes

HES1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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