Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism.

Genome biology - 20 Dec 2011

Meister Peter, Schott Sonia, Bedet Cécile, Xiao Yu, Rohner Sabine, Bodennec Selena, Hudry Bruno, Molin Laurent, Solari Florence, Gasser Susan M, Palladino Francesca

Abstract excerpt

BACKGROUND: Heterochromatin protein 1 (HP1) family proteins have a well-characterized role in heterochromatin packaging and gene regulation. Their function in organismal development, however, is less well understood. Here we used genome-wide expression profiling to assess novel functions of the Caenorhabditis elegans HP1 homolog HPL-2 at specific developmental stages. RESULTS: We show that HPL-2 regulates the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to Germ Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hermaphroditic Organisms

Share to Heterochromatin

Share to Lipid Metabolism

Share to Longevity

Share to Receptor, Insulin

Share to Transforming Growth Factor beta

Source

Open in PubMed Open full text

Identifiers

PMID: 22185090
DOI: 10.1186/gb-2011-12-12-r123
PMCID: PMC3334618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism.PMID 22185090Read ↗

Unique and redundant functions of C. elegans HP1 proteins in post-embryonic development.Semantic proximity Read ↗

The Caenorhabditis elegans HP1 family protein HPL-2 maintains ER homeostasis through the UPR and hormesis.Semantic proximity Read ↗

Transcriptional repression of Hox genes by C. elegans HP1/HPL and H1/HIS-24.Semantic proximity Read ↗

Antagonistic functions of SET-2/SET1 and HPL/HP1 proteins in C. elegans development.Semantic proximity Read ↗

DAF-12 germline-to-soma signaling mediates transgenerational longevity in <i>C. elegans</i>Semantic proximity Read ↗

The large isoform of Drosophila melanogaster heterochromatin protein 2 plays a critical role in gene silencing and chromosome structure.Semantic proximity Read ↗

The histone chaperone activity of SPT2 controls chromatin structure and function in MetazoaSemantic proximity Read ↗

The zinc-finger transcription factor LSL-1 is a major regulator of the germline transcriptional program in <i>C. elegans</i>Semantic proximity Read ↗

A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stressSemantic proximity Read ↗

The TRIM-NHL protein NHL-2 is a Novel Co-Factor of the CSR-1 and HRDE-1 22G-RNA PathwaysSemantic proximity Read ↗

GLD-2/RNP-8 cytoplasmic poly(A) polymerase is a broad-spectrum regulator of the oogenesis programSemantic proximity Read ↗

<i>Caenorhabditis elegans</i> germline development requires <i>brap-2</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.