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Article

Angiogenesis related genes NOS3, CD14, MMP3 and IL4R are associated to VEGF gene expression and circulating levels in healthy adults.

BMC medical genetics - 5 Oct 2015

Saleh Abdelsalam, Stathopoulou Maria G, Dadé Sébastien, Ndiaye Ndeye Coumba, Azimi-Nezhad Mohsen, Murray Helena, Masson Christine, Lamont John, Fitzgerald Peter, Visvikis-Siest Sophie

Abstract excerpt

BACKGROUND: Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis. The aim was to assess the genetic connections between the angiogenesis-related NOS3, CD14, MMP3, IL4R, IL4 genes and VEGF expression and plasma levels. METHODS: The associations between VEGF plasma levels with the polymorphisms of NOS3, CD14, MMP3, IL4R, and IL4 were assessed in 403 healthy unrelated adults. The epistatic and...

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Source

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Identifiers

PMID: 26437765
DOI: 10.1186/s12881-015-0234-6
PMCID: PMC4594922

Genes

MMP3
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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