Article
Effect of p53 gene polymorphism on functions of prostate cancer cells.
Genetics and molecular research : GMR - 2 Oct 2015
Chi N, Yun Z Z, Tan Z H, Li X Z, Chen B T B G, Liu J, Xu L B, Ma K W, Li S X, Liu J F, Liu C X
Abstract excerpt
Prostate cancer cells were transfected with plasmids [empty plasmids, wild-type pcDNA3.1-p53 (V/V), mutant type pcDNA3.1- p53 (G/G)] to analyze the effect of p53 gene polymorphisms on the proliferation, cycle, and apoptosis of prostatic cancer cells. Empty plasmids containing wild-type pcDNA3.1-p53 (V/V) and mutant type pcDNA3.1- p53 (G/G) were used to transfect PC3 and LNCaP cells, respectively. Cell...
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