Article
Prediction of Blood Pressure and Blood Pressure Change With a Genetic Risk Score.
Journal of clinical hypertension (Greenwich, Conn.) - 1 Mar 2016
Niiranen Teemu J, Havulinna Aki S, Langén Ville L, Salomaa Veikko, Jula Antti M
Abstract excerpt
The authors investigated whether a genetic risk score (GRS) constructed of 32 single nucleotide polymorphisms would predict incident hypertension and blood pressure (BP) change over time in a population cohort during an 11-year follow-up (n=5402 at baseline, 3266 at follow-up). In multivariable models, GRS was associated with higher systolic/diastolic BP values at baseline (β±standard error [SE],...
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