Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular modeling, mutational analysis and conformational switching in IL27: An in silico structural insight towards AIDS research.

Gene - 15 Jan 2016

Banerjee Arundhati, Ray Sujay

Abstract excerpt

The advancement in proteomics and bioinformatics provokes to discern the molecular-level probe for HIV inhibitor; human interleukin-27 (IL27). Documentation documents that tyrosine residues in IL27 play a pivotal role for interacting with HIV, causing apoptosis of the HIV+ cells. Primarily, 3D structure of human wild-type (WT) IL27 was built through manifold molecular modeling techniques after the satisfaction of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukins

Share to Models, Molecular

Share to Mutation

Share to Protein Folding

Share to Protein Structure, Tertiary

Source

Identifiers

PMID: 26432006
DOI: 10.1016/j.gene.2015.09.075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular modeling, mutational analysis and conformational switching in IL27: An in silico structural insight towards AIDS research.PMID 26432006Read ↗

An integrated mutation-based immunoinformatic approach incorporating variability in epitopes: a study based on HIV subtype CSemantic proximity Read ↗

Multiple interests in structural models of DARC transmembrane protein.Semantic proximity Read ↗

Flexible regions govern promiscuous binding of IL ‐24 to receptors IL ‐20R1 and IL ‐22R1Semantic proximity Read ↗

Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27Semantic proximity Read ↗

Accurate structure prediction of peptide-MHC complexes for identifying highly immunogenic antigens.Semantic proximity Read ↗

Structure of IL-17A in Complex with a Potent, Fully Human Neutralizing AntibodySemantic proximity Read ↗

Integrated analysis of residue coevolution and protein structures capture key protein sectors in HIV-1 proteins.Semantic proximity Read ↗

Mutational Analysis of Interleukin-11 and its Consequences on Cancer and COVID-19 Related Cytokine Storm -An Extensive Molecular Dynamics StudySemantic proximity Read ↗

IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants.Semantic proximity Read ↗

In Silico binding of human immunodeficiency virus (HIV) with STRA6 could explain the mystery of the immunodeficiency caused by HIV infection. An exciting breakthrough in molecular docking and VirologySemantic proximity Read ↗

Detection of HIV-1 matrix protein p17 quasispecies variants in plasma of chronic HIV-1-infected patients by ultra-deep pyrosequencing.Semantic proximity Read ↗

Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 1 Matrix Proteins Specify Different Capabilities To Modulate B Cell GrowthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.