Article
Genetic variation in Micro-RNA genes of host genome affects clinical manifestation of symptomatic Human Cytomegalovirus infection.
Human immunology - 1 Oct 2015
Misra Maneesh Kumar, Mishra Aditi, Pandey Shashi Kant, Kapoor Rakesh, Sharma Raj Kumar, Agrawal Suraksha
Abstract excerpt
BACKGROUND: Micro-RNAs are implicated in various physiological and pathologic processes. In this study, we tested whether Micro-RNA gene variants of host-genome affect clinical manifestation of symptomatic HCMV infection. METHODOLOGY: HCMV infection was detected by fluorescent PCR and immuno-histochemistry. The detection of genetic variants of four studied Micro-RNA tag-SNPs was done through PCR-RFLP assay and...
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