Article
Association of miR-146a rs2910164 with childhood IgA nephropathy.
Pediatric nephrology (Berlin, Germany) - 1 Oct 2014
Lin Junhong, Huang Yao, Zhang Xuelin, Chen Junbin, Sheng Haihui
Abstract excerpt
BACKGROUND: Micro-RNAs (miRNAs) play important roles in the regulation of immune response and inflammation. The purpose of this study was to investigate the association between three single nucleotide polymorphisms (SNPs) (mir-146a rs2910164, let-7a-2 rs1143770, miR-196a2 rs11614913) and susceptibility to and severity of childhood immunoglobulin A (IgA) nephropathy (IgAN). METHODS: We genotyped three miRNA SNPs...
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