Article
Myosin Vb gene is associated with schizophrenia in Chinese Han population.
Psychiatry research - 15 May 2013
Chen Yaguang, Tian Lin, Zhang Fuquan, Liu Chenxing, Lu Tianlan, Ruan Yanyan, Wang Lifang, Yan Hao, Yan Jun, Liu Qi, Zhang Hongyan, Ma WenBin, Yang Jianli, Li Keqing, Lv Luxian, Zhang Dai, Yue Weihua
Abstract excerpt
Myosin Vb (MYO5B) has recently been implicated in the etiology of bipolar disorder in a genome-wide association study (GWAS). This gene is involved in amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor subunit glutamate receptor 1 (GluR1) recycling and plays an important role in the primary excitatory neurotransmission. Dysfunction of the brain glutamate system has been postulated to be involved...
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