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Article

Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell-Mediated Tumor Control in the Genital Tract.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2016

Sun Yun-Yan, Peng Shiwen, Han Liping, Qiu Jin, Song Liwen, Tsai Yachea, Yang Benjamin, Roden Richard B S, Trimble Cornelia L, Hung Chien-Fu, Wu T-C

Abstract excerpt

PURPOSE: Two viral oncoproteins, E6 and E7, are expressed in all human papillomavirus (HPV)-infected cells, from initial infection in the genital tract to metastatic cervical cancer. Intramuscular vaccination of women with high-grade cervical intraepithelial neoplasia (CIN2/3) twice with a naked DNA vaccine, pNGVL4a-sig/E7(detox)/HSP70, and a single boost with HPVE6/E7 recombinant vaccinia vaccine (TA-HPV)...

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Identifiers

PMID: 26420854
DOI: 10.1158/1078-0432.CCR-15-0234
PMCID: PMC4738102

Genes

CCR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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