Article
A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2015
Zhu Guangjing, Liu Zhi, Epstein Jonathan I, Davis Christine, Christudass Christhunesa S, Carter H Ballentine, Landis Patricia, Zhang Hui, Chung Joon-Yong, Hewitt Stephen M, Miller M Craig, Veltri Robert W
Abstract excerpt
BACKGROUND: Early prediction of disease progression in men with very low-risk (VLR) prostate cancer who selected active surveillance (AS) rather than immediate treatment could reduce morbidity associated with overtreatment. METHODS: We evaluated the association of six biomarkers [Periostin, (-5, -7) proPSA, CACNA1D, HER2/neu, EZH2, and Ki-67] with different Gleason scores and biochemical recurrence (BCR) on...
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