Article

Identifying patients with rapid progression from hormone-sensitive to castration-resistant prostate cancer: a retrospective study

2022-10-24

Abstract excerpt

<h4>Background</h4> Prostate cancer (PCa) is the second most prevalent malignancy and the fifth cause of cancer-related deaths in men. A crucial challenge is identifying the population at risk of rapid progression from hormone-sensitive PCa (HSPC) to the lethal castration-resistant PCa (CRPC). <h4>Methods</h4> We collected 78 HSPC biopsies and measured their proteomes using pressure cycling technology and a pulsed...

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Literature Corpus work: b9281200-2fc4-58f7-926f-02294c8059e3
DOI: 10.1101/2022.10.23.22281406

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