Article
Impact of follicle-stimulating hormone receptor variants in female infertility.
Journal of assisted reproduction and genetics - 1 Nov 2015
Ilgaz Nermin Seda, Aydos Oya Sena Erdogan, Karadag Aynur, Taspinar Mehmet, Eryilmaz Ozlem Gun, Sunguroglu Asuman
Abstract excerpt
PURPOSE: Follicle-stimulating hormone (FSH) and its receptor play a major role in the development of follicles and regulation of steroidogenesis in the ovary and spermatogenesis in the testis. We aim to analyze the role of FSHR gene variants (single nucleotide polymorphisms (SNPs) in exon 10 (codon 307 and 680) and in the core promoter region (at position -29) and Ala189Val inactivating mutation) in Turkish...
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