Article
FSH receptor gene polymorphisms in fertile and infertile Italian men.
Reproductive biomedicine online - 1 Dec 2006
Pengo Manuel, Ferlin Alberto, Arredi Barbara, Ganz Francesco, Selice Riccardo, Garolla Andrea, Foresta Carlo
Abstract excerpt
In women, single nucleotide polymorphisms (SNP) of the FSH receptor (FSHR) gene influence FSH concentrations and the sensitivity of the FSHR to FSH in vivo. In contrast, the significance of FSHR R gene SNP in the male is poorly understood. To this aim, the possible role of three FSHR SNP was evaluated in male infertility. SNP in exon 10 (codon 307 and 680) and in the core promoter region (at position -29) of the...
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