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Article

MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

29 Apr 2009

Abstract excerpt

Detailed genomic studies have shown that cytogenetic abnormalities contribute to multiple myeloma (MM) pathogenesis and disease progression. Nevertheless, little is known about the characteristics of MM at the epigenetic level and specifically how microRNAs regulate MM progression in the context of the bone marrow milieu. Therefore, we performed microRNA expression profiling of bone marrow derived CD138(+) MM...

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Identifiers

PMID: 19401561
DOI: 10.1182/blood-2009-01-198408

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